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Penetratin是一种源自触角蛋白的细胞穿透肽
CAS编号:214556-79-3
分子量:2360.9
分子式:C104H169N35O19S·C2HO2F3
Penetratin是一种细胞穿透肽(cell-penetrating peptide),也称为蛋白质转导结构域(protein transduction domain/PTD),其中前16个氨基酸来自触角蛋白同源结构域的第三螺旋。与磷酸二酯寡核苷酸连接的Penetratin能够穿透神经元细胞膜和下调基因。
序列:RQIKIWFQNRRMKWKKGG
The highly efficient cell-penetrating peptide penetratin derived from the third helix of the Antennapedia protein homeodomain also showed antimicrobial and antifungal activity.